About Resonance Genomics
Resonance Genomics develops structured genomic evidence infrastructure designed to support internal laboratory review, assay evaluation, transcript-aware genomic organization, and phenotype-driven variant review workflows.
The infrastructure is designed to complement existing laboratory processes through reproducible, research-use-oriented workflow support using current public genomic resources and transcript frameworks.
Resonance Genomics workflows are informed by prior experience in clinical and diagnostic genomics environments involving variant review, assay-development support, transcript-aware genomic analysis, and structured genomic evidence evaluation workflows.
Current RG infrastructure and workflows are independently developed for research-use-oriented laboratory support and genomic review applications.
The focus is on non-interpretive infrastructure that enables laboratories and research groups to organize and evaluate genomic evidence within their existing workflows.
Based in Canada.
Operating Principles
Resonance Genomics workflows are designed around several core principles:
- transcript-consistent genomic coordinate handling
- reproducible and version-aware workflow design
- explicit attribution to underlying public genomic resources
- structured evidence organization rather than clinical interpretation
- support for laboratory review workflows across GRCh37 and GRCh38 contexts
- separation between research-use infrastructure support and clinical decision-making
Workflow Areas
Current workflow development focuses on infrastructure supporting laboratory evaluation in areas such as:
- large-scale GRCh38-aware primer QC workflows
- intronic and splice-adjacent variant review support
- capture design review and transcript-aware BED evaluation
- structured literature-linked variant evidence
- risk-allele evidence extraction from public resources
Operational Boundaries
Resonance Genomics does not provide clinical interpretation, diagnostic reporting, pathogenicity classification, or medical advice.
All Resonance Genomics workflows are designed to support research-use and internal laboratory evaluation workflows. Outputs are intended to assist structured genomic evidence review and assay-support activities within established laboratory environments. Laboratories remain responsible for all downstream validation, interpretation, and clinical use within their own governance frameworks.